Fan de l'acide borique aussi. Petite mise en garde sur l'exposition prolongee, mais a des doses normalement ayant peu de sens en milieu domestique. Mais bon, C'est REACH quand meme.
Pour ceux qui s'inquieterait, se poserait des questions, etc (english wiki, sorry):
Toxicology[edit]
Based on mammalian
median lethal dose (LD50) rating of 2,660 mg/kg body mass, boric acid is only poisonous if taken internally or inhaled in large quantities. The Fourteenth Edition of the
Merck Index indicates that the LD50 of boric acid is 5.14 g/kg for oral dosages given to rats, and that 5 to 20 g/kg has produced death in adult humans. For comparison's sake, the LD50 of
salt is reported to be 3.75 g/kg in rats according to the
Merck Index. According to the
Agency for Toxic Substances and Disease Registry, "The minimal lethal dose of ingested boron (as boric acid) was reported to be 2–3 g in infants, 5–6 g in children, and 15–20 g in adults. [...] However, a review of 784 human poisonings with boric acid (10–88 g) reported no fatalities, with 88% of cases being asymptomatic."
[11]
Long-term exposure to boric acid may be of more concern, causing kidney damage and eventually kidney failure (see links below). Although it does not appear to be
carcinogenic, studies in dogs have reported
testicular atrophy after exposure to 32 mg/kg bw/day for 90 days. This level is far lower than the LD50.
[12]
According to the boric acid IUCLID Dataset published by the European Commission, boric acid in high doses shows significant developmental toxicity and
teratogenicity in rabbit, rat, and mouse fetuses as well as cardiovascular defects, skeletal variations, and mild kidney lesions.
[13] As a consequence in the 30th ATP to EU directive 67/548/EEC of August 2008, the European Commission decided to amend its classification as
reprotoxic category 2, and to apply the
risk phrases R60 (may impair fertility) and R61 (may cause harm to the unborn child).
[14][15][16][17][18]
At a 2010 European Diagnostics Manufacturing Association (EDMA) Meeting, several new additions to the Substance of Very High Concern (SVHC) candidate list in relation to the
Registration, Evaluation, Authorisation and Restriction of Chemicals Regulations 2007 (REACH) were discussed. Following the registration and review completed as part of REACH, the classification of Boric Acid CAS 10043-35-3 / 11113-50-1 is listed from 1 December 2010 is
H360FD (May damage fertility. May damage the unborn child.)[19][20]
Insecticidal[edit]
Boric acid was first registered in the US as an insecticide in 1948 for control of
cockroaches,
termites,
fire ants,
fleas,
silverfish, and many other
insects. The product is generally considered to be safe to use in household kitchens to control cockroaches and ants.
[31] It acts as a stomach poison affecting the insects'
metabolism, and the dry powder is
abrasive to the insects'
exoskeletons. Boric acid also has the reputation as "the gift that keeps on killing" in that roaches that cross over lightly dusted areas do not die immediately, but that the effect is like shards of glass cutting them apart. This often allows a roach to go back to the nest where it soon dies. Cockroaches, being
cannibalistic, eat others killed by contact or consumption of boric acid, consuming the powder trapped in the dead roach and killing them, too. The cycle continues until the boric acid has more-or-less been exhausted or the queen herself has consumed some, killing her, which destroys the colony.
[31]
,la guerre ,est fini.............
